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Dr. Xiao-Song Xue (薛小松)-Associate Professor: Xiao-Song Xue was born in 1983 in Chongqing. He received his PhD in organic chemistry from Nanking University in 2013 under the supervision of Prof. Jin-Pei Cheng. In the same year, he joined Nanking University as an Assistant Professor and was promoted to Associate Professor in 2016. He was a Visiting Scholar in Prof. Kendall N. Houk group at University of California, Los Angeles in 2017-2020. His current research interests include: 1) Reactivity and Selectivity Rules in Organic Reactions; 2) Reaction Dynamics, and 3) The Chemistry of the Halogens. His work has been published in Chem. Rev., Acc. Chem. Res., J. Am. Chem. Soc., Angew. Chem. Int. Ed., Nat. Chem., Nat. Commun., Org. Lett., J. Org. Chem., etc.


  1. [1] Man Li, Xiao-Song Xue*, Jin-Pei Cheng, Establishing for Cation and Radical Donor Ability Scales of Electrophilic F, CF3, and SCF3 transfer reagents, Acc. Chem. Res. 2020, 53, 182−197.

  2. [2] Mingyang Wang, Man Li, Shan Yang, Xiao-Song Xue*, Xinxin Wu & Chen Zhu*, Radical-mediated CC cleavage of unstrained cycloketones and DFT study for unusual regioselectivity, Nat. Commun., 2020, 11, 672.

    [3] Hanliang Zheng, Yueqian Sang, K. N. Houk*, Xiao-Song Xue*, Jin-Pei Cheng, Mechanism and Origins of Enantioselectivities in Spirobiindane-based Hypervalent Iodine(III) Induced Asymmetric Dearomatizing Spirolactonizations, J. Am. Chem. Soc. 2019. 141, 16046-16056.

  3. [4] Honggui Lv, Huiying Kang, Biying Zhou, Xiao-Song Xue,* Keary Engle,* and Dongbing Zhao* Nickel-catalyzed intermolecular oxidative Heck arylation driven by transfer hydrogenation, Nat. Commun., 2019, 10, 5025.

  4. [5] Xia-Ping Fu,# Xiao-Song Xue,# Xue-Ying Zhang, Yu-Lan Xiao, Shu Zhang, Yin-Long Guo, Xuebing Leng, K. N. Houk*, Xingang Zhang*, Controllable Catalytic Difluorocarbene Transfer Enables Access to Diversified Fluoroalkylated Arenes, Nat. Chem. 2019, 11, 948–956. (# equally contribution)

  5. [6] Jiahang Lv, Xiangyang Chen , Xiao-Song Xue , Binlin Zhao , Yue Zhao , Yi Lu , Jing Zhao , Wei-Yin Sun , Yong Liang, K. N. Houk*,Zhuangzhi Shi,* Metal-free directed C-H bond activation and borylation, Nature, 2019. 575, 336-340.

  6. [7] Xiao-Song Xue,# Cooper S. Jamieson,# Marc Garcia-Borràs,# Xiaofei Dong,# Zhongyue Yang, K. N. Houk. Ambimodal Trispericyclic Transition State and Dynamic Control of Periselectivity. J. Am. Chem. Soc. 2019. 141, 1217. (# equally contribution)

  7. [8] Biying. Zhou, Moriana K. Haj, Eric N. Jacobsen, Houk, K. N.,* Xiao-Song Xue,* Mechanism and Origins of Chemo- and Stereoselectivities of Aryl Iodide-Catalyzed Asymmetric Difluorinations of β-Substituted Styrenes, J. Am. Chem. Soc. 2018, 140, 15206.

  8. [9] Jingjing Zhang; Yang Jin-Dong; Hanliang Zheng; Xue, Xiao-Song;* Herbert Mayr;* Jin-Pei Cheng. Exploration of the Synthetic Potential of Electrophilic Trifluoromethylthiolating and Difluoromethylthiolating Reagents. Angew. Chem. Int. Ed. 2018, 57, 12690.

  9. [10] Li, Man; Xue, Xiao-Song;* Cheng, Jin-Pei. Mechanism and Origins of Stereoinduction in Natural Cinchona Alkaloid Catalyzed Asymmetric Electrophilic Trifluoromethylthiolation of β-Ketoesters with N-Trifluoromethylthiophthalimide as Electrophilic SCF3 Source. ACS Catal., 2017, 7, 7977.

  10. [11] Xue, Xiao-Song;# Ji, Pengju,# Zhou, Biying; Cheng, Jin-Pei*. The Essential Role of Bond Energetics in C–H Activation/Functionalization. Chem. Rev. 2017, 117, 8622. (# equally contribution)

Last Update : 2020-09-25 |